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This binding site is deeply buried within the core of the transporter protein and is structurally formed by amino acids located on Transmembrane Helices (TMHs) 1, 3, 6, and 8 (Beuming et al., 2008

[DOI] [PubMed] [Google Scholar] 84.Lv Z., Fan H., Song B., Li G., Liu D., Guo Y

This allows the body time to respond to the injection and ensures any mild side effects have settled before travelling
