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Abbreviations PD Parkinsons disease -Syn -Synuclein ROS Reactive oxygen species GSH Glutathione GSH-Px Glutathione peroxidase PUFA Polyunsaturated fatty acid GPX4 Glutathione peroxidase 4 MDA Malondialdehyde BJP-IVb Buddlejasaponin IVb IRP2 Iron regulatory protein 2 GAA Ganoderic acid A LC3B Light chain 3B NCOA4 Nuclear Receptor Coactivator 4 FTH1 Ferritin heavy chain 1 DA Dopamine BJP-IVb Buddlejasaponin IVb LC3 Light chain 3 LDs Lipid droplets FMT Fecal microbiota transplantation Neo Neoeriocitrin ASH Acanthopanax senticosus TH Tyrosine hydroxylase CA Chicoric acid PPDs Protopanaxadiols Cyt C Cytochrome C Bax Bcl-2-associated X protein SalB Salvianolic acid B ERS Endoplasmic reticulum stress CNS Central nervous system BBB Bloodbrain barrier IL-6 Interleukin-6 IL-10 Interleukin-10 TNF- Tumor necrosis factor-alpha CSE C