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All methods have advantages and disadvantages but have given valuable insights into the subcellular distribution of glutathione
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Mechanistically, FAS is required for macrophage membrane remodeling: a loss of FAS resulted in modifications in the plasma membrane composition and Rho GTPase trafficking, which attenuated macrophage inflammatory signaling (Wei et al., 2016)

This suggests increased PLP expression may be involved in the remyelination process, as PLP is a key component of the myelin sheath [64]
