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Nasal Sprays : Nasal B12 sprays have been shown to effectively raise B12 levels and offer a convenient, needle-free alternative for individuals who prefer non-injection options or have difficulty with traditional supplementation[23]

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It influences the nitric-oxide (NO) system and the dopaminergic and serotonergic systems, which is why anti-inflammatory and gut-brain-axis effects also appear in the literature

An intervention trial in 75 adult male smokers found that supplementation with 1,000 mg/day of vitamin C resulted in significantly lower blood lead concentration over a four-week treatment period compared to placebo (219)

Third, over 50% of individuals with symptomatic B deficiency test negative for IF or parietal cell auto-antibodies, and the true prevalence of AIG in the UK is not known, as individuals with B deficiency rarely undergo endoscopy

Meadows protocol, and some reported positive effects