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Furthermore, oxidative stress can impede the nucleoplasmic translocation of pancreaticoduodenal homeobox factor 1 (PDX-1), impair energy metabolism, and reduce insulin production and release (Duni et al., 2019)

These products help achieve a more even tone and reduce dark spots, but results require ongoing maintenance

Mitochondria are involved in the RCD process of apoptosis, which indicates that NiO NPs can induce apoptosis in yeast which is dependent on caspase and mitochondria

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Therefore, rational combined immune checkpoint inhibitors with ferroptosis inducers are essential for enhancement of cancer immunotherapy

Nanomedicine 5 (3), 379396 (2010)