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The demonstration that OEA is the most active endogenous ligand for GPR119 is of particular interest since previous work has demonstrated that OEA, when administered to laboratory animals, causes a significant reduction in food intake and body weight gain

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This dual role explains its broad biological impact, from lungs to brain to metabolism

doi: 10.1186/s40035-020-00221-2

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Specifically, the ratio of total fat and protein to energy intake was significantly linked to depressive symptoms in Hispanics, dietary fiber to sugar ratio in whites, total energy intake in blacks, and total sugar to dietary fiber ratio in Asians