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Powder X-ray diffraction (PXRD) analyses of APTES-COF-1 revealed maintained crystallinity post-functionalization, with distinct (110), (201), and (002) diffraction planes confirming structural integrity during drug encapsulation [145]

This effect of AMPK signaling is in agreement with our previous studies showing that, despite having 15% and 40% of WT total and mitochondrial GSH levels (respectively), livers from nave GCLM KO mice maintain structural and functional integrity of the mitochondria and show induction of ER stress-related genes 17,38

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