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Edematous cellulite : The third-degree cellulite condition is uncommon but unbearably painful and severe

5-amino-1MQ, an analogue from our initial series of NNMT inhibitors with low IC 50 value (IC 50 = ~1 M;[17]), and high cell membrane permeability (Table 2), produced the greatest reduction of intracellular 1-MNA levels at a concentration of 10 M among tested inhibitors (Figure 2D)

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Future studies will be focused on optimizing the MQ-scaffold lead series to generate more potent NNMT inhibitors with significantly improved drug-like ADME profile

Treatment Cycle: Daily for 20 Days Timing of dose: In Morning- 30 mins prior to eating