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The competition between NA methylation and NAD + salvage indicates that NNMT might limit fuel oxidation and promote fat storage, because if the activity or expression of NNMT is high, then, NA might not be salvageable, thus limiting the NAD + -dependent processes [16]

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Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper

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