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A smaller placebo-controlled trial showed that oral administration of 300 mg/day of coenzyme Q 10 for 48 to 96 months moderately improved motor symptoms in treated patients (with Levodopa) with re-emerging symptoms but not in patients at an early stage of the disease (67)

, Habibey, R

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Autonomic neuropathy, a component of DPN, can lead to abnormalities in HRV and elevate the risk of silent myocardial ischemia, particularly in patients with T2DM

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As an electron shuttle, MB can substitute for natural cofactors in redox reactions due to its favorable redox potential (Nedu et al