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In an attempt to minimize the onset of oxidative stress, supplementation with various known antioxidants has been suggested

2.1 Oxidative stress and ethanol metabolites Alcohol is metabolized in the liver by alcohol dehydrogenase (ADH), cytochrome P450 2E1 (CYP2E1), and catalase, concurrently generating reactive oxygen species (ROS) and leading to oxidative stress (Yang et al., 2022)

146 Hypoglossal nerve stimulation may be helpful for individuals with obstructive sleep apnea who fail to respond to CPAP, and greater improvements in AHI can be expected for those with more severe disease, older age, and lower BMI

Most importantly, consult your dermatologist about your complete medical history before starting treatment

2 Search criteria and data sources The literature search was conducted using a structured strategy, as summarized in Table 1