glutathione stransferase a1 The Multifaceted Role of S-Transferases in Health and Disease Mouse GSTA1 (Glutathione S-transferase A1)
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[Abstract]2021 Oct 29;e2104359

doi: 10.1016/j.celrep.2018.03.076 62 NittaMKozonoDKennedyRStommelJNgKZinnPOet al

Grip strength increased by approximately 60% when the compound was combined with rigorous exercise training, compared to about 25% improvement from either exercise or treatment alone

Mechanistically, a key way MOTS-c influences fat metabolism is through its upstream activation of AMPK and downstream effects on gene expression
