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Signaling of TGF- also involves the Spp1 gene product osteopontin

Findings include: Accelerated wound closure rates in multiple animal models across all regenerative components KPV-mediated inflammation control: Reduced inflammatory cell infiltration (leukocytes, mast cells) Enhanced re-epithelialization and granulation tissue formation Improved collagen deposition and organization in healing wounds Smaller scar formation demonstrated in KPV studies, complementing tissue repair components Antimicrobial effects from KPV against S