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Efficacy and safety of plasma exchange with 5% albumin to modify cerebrospinal fluid and plasma amyloid- concentrations and cognition outcomes in Alzheimers disease patients: a multicenter, randomized, controlled clinical trial

[DOI] [PubMed] [Google Scholar] 48.Bhlmann N., Leuthuser K., Muff R., Fischer J.A., Born W

This topic has mainly not been of interest for recent work and well-designed trials with objective circadian parameters are few

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Instructions for sample collection and handling are as follows: When it is necessary to perform cytoreductive therapy with the use of corticosteroids or chemotherapy, it is recommended that material first be collected by incisional biopsy, considering that cytoreductive protocols can change the assessment of the cell proliferation index (mitotic count and immunohistochemical analysis for Ki67), and when possible, the excised formation should be reassessed