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HIEs support the mobilization of health care information electronically across organizations within a region, community or hospital system, for example from hospitals to health departments

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The key to the initiation of EBV lysogenic replication is the expression of immediate early genes (IEs), including BZLF1 (Zta) 15 and BRLF1 (Rta) 16

37 JiangY.DaiY.LiuZ.LiaoY.SunS.KongX.et al (2023)

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This could be a key mechanism by which IGFBP-3, IGFBP-5 and possibly other IGFBPs can regulate the balance between cell death and survival in response to certain cancer therapies