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3 Physiological mechanisms of exercise-induced fatigue 3.1 Oxidative stress and free radical production This means that high-intensity exercise induces a substantial generation of Reactive oxygen species (ROS)

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Gisslinger H, Kurzrock R, Gisslinger B, Jiang S, Li S, Virgolini I, Woloszczuk W, Andreeff M , Talpaz M

While chronic NSAID use is associated with interstitial nephritis, nephritic syndrome, or analgesic nephropathy, acute overdose can cause gastric injury and is sometimes accompanied by a reversible azotemia caused by vasoconstriction from decreased prostaglandin production (28)

International Review of Neurobiology, 100 , 127149

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