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Niacin is involved in the DNA metabolism and repair, cellular signaling events, cell migration [24], and decreases the expression of the pro-inflammatory cytokines, IL-1, IL-6, and TNF- by the macrophages [25]

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When you're deficient in B12, you may be more susceptible to infections

Its suggested to give this dose daily or every other day for one to two weeks to effectively address the deficiency