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However, under more extreme conditions such as: 1) inadequate intake of foodstuffs containing the antioxidants, 2) excessive intake of pro-oxidants, 3) exposure to noxious chemicals or ultraviolet light, 4) injury/wounds, and/or 5) intense exercise, especially eccentric exercise, the body's endogenous antioxidant system is not able to effectively remove excessive ROS production[2]

Chem , 272, 1404114044

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Sample was eluted in gradient elution mode using solvent A (0.1% formic acid in water) and solvent B (0.1% formic acid in ACN)

In addition, IRI serves as a widely utilized experimental animal AKI model [26]

Kojic Acid: A natural compound derived from fungi, kojic acid is known for its powerful skin-lightening properties