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Histologically, chronic pefloxacin treatment increased the ratio of cells with round nuclei, a phenomenon seen in tendinopathy (Figures 4D, E)

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274 Antagonizing LPAR1/3 in db/db and STZ-induced T1D models reduced GSK3 phosphorylation, SREBP1 nuclear translocation, and TGF- expression, thereby limiting fibrosis and renal injury
