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Z 1 is H, (C 1 -C 5 ) alkyl, or phenyl optionally substituted with one, two, or three groups of (C 1 -C5) alkyl, (C 1 -C5) alkoxy, (C 1 -C 4 ) thioalkoxy, halogen, nitro, COOR, ONHR, -O(CH 2 ) n COOR, -S(CH 2 ) n COOR, -O(CH 2 ) n CONHR, or - S(CH 2 ) n CONHR wherein n and R are as defined above

Unfortunately, one-third of cancer patients succumb to the disease within five years of diagnosis, primarily due to tumor recurrence [1, 6]

Check with a doctor if youre pregnant, have a medical condition, or are taking medication
