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Clinical observations of patients have indicated that long-term exposure to high doses of propofol (surpassing 45 mgkg 1 h 1 and lasting over 48 h) can induce propofol infusion syndrome (PRIS) by damaging mitochondrial complexes II and IV in the muscles [30]

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Available online: [PubMed] [Google Scholar] 15.Gonzalez A.C., Costa T.F., Andrade Z.A., Medrado A.R

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doi: 10.1111/imm.12163 263 PengB.XuC.WangS.ZhangY.LiW