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These data all support that enhancing PDHC activity and maintaining metabolism homeostasis can restore mitochondrial function and inhibit organ dysfunction in sepsis

Meng Q, Wang A, Hua H, Jiang Y, Wang Y, Mu H, Wu Z, Sun K

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Potential applications encompass adjunctive treatment for Candida albicans infections, topical anti-inflammatory agents, moisturizers, and permeability enhancers in cosmetic formulations, and dietary oil substitutes for managing hypertriglyceridaemia and metabolic disorders affecting the liver and brain

doi:10.1073/pnas.2110610118

Notably, the ESX-4 secretion system is transcriptionally activated in the recipient on donor contact and is essential for DCT (58)