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Due to the relatively high binding affinity of ferrozine for Fe 2+ ions, many studies have used stoichiometric amounts of ferrozine, or a slight excess of chelator, to ensure that Fe 2+ ions are fully bound

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Clinical consequences include spider telangiectasias and palmar erythema, gynecomastia in men, and abnormal vaginal bleeding and irregular menstrual periods in women

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Abbreviations The following abbreviations are used in this manuscript: Supplementary Materials The following supporting information can be downloaded at: Supplementary Table S1

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