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Lack of Nrf2 in this model also restored basal protein oxidation levels (measured by an increase in 4-hydroxynonenal modification, a byproduct of lipid peroxidation)

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In contrast, in patients with congenital hypothyroidism in areas without iodine deficiency treated with 20-60 ug selenomethionine for 3 months (68), Se supplementation was found to reduce serum thyroglobulin

The drug needs to be proven to work for a specific disease indication to get approval, while BPCs effects seem to be pleiotropic and the research cannot seem to focus on one, singular disease case to focus on

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Short answer: If you can absorb B12, high-dose oral B12 (1,0002,000 mcg/day) is as effective as intramuscular injections for normalizing levels in most people (AAFP