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The most common B12/MIC side effect is pain, redness, or itching at the injection site

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Some medications used for acid reflux or diabetes may also lower vitamin B12 levels over time

If semaglutide or tirzepatide produce significant weight loss that you maintain, the health benefits (reduced diabetes risk, improved cardiovascular health, better mobility) provide substantial long-term value

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Other symptoms include headaches and loss of taste
