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The quadruplet regimen Dara-VRd (Daratumumab + Bortezomib + Lenalidomide + Dexamethasone) has recently shown superior response rates, higher minimal residual disease (MRD) negative rates, and improved progression-free survival in newly diagnosed multiple myeloma patients

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The gluteal region can be used but requires careful anatomical knowledge to avoid neurovascular structures, including the sciatic nerve and gluteal arteries

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