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Thats different from pretending theres no data. Theres preclinical data, animal studies, human case reports, and in some cases small clinical trials

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Case example : A patient receives creation of arteriovenous fistula for dialysis

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Undoubtedly, experiments on the Brennan rodent paw incision model have contributed significantly to the existing knowledge on postoperative pain [7, 8]

Phase 2 trial (NEJM 2023) randomized 338 adults with obesity to retatrutide doses from 1 mg to 12 mg/week