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FXR regulates adipose tissue remodeling during obesity

187 The PDE4 inhibitor roflumilast has been approved by the Food and Drug Administration as a COPD treatment

10.1016/j.ajem.2018.03.005 78 PrinceM

Saunders J, Hall SHE, Sonksen PH

All treatments were per os and for 14 days
At the same time, molecules with multiple hydroxyl groups, especially in the B-ring, significantly increased the amount of hydroxyl radicals in the Fenton reaction [36]
