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In a rat model, our previous research on early NHPN-1010 treatment for blast-induced tinnitusspecifically targeting cochlear synaptopathydemonstrated that (1) blast overpressure caused a permanent loss of cochlear nerve ribbon synapses (RSs), and (2) administration of NHPN-1010 within 3 days of blast trauma, compared to placebo, significantly rescued RSs, as evidenced by ribbon counts in cochlear histological analyses and corresponding functional changes in suprathreshold wave-I amplitudes of the auditory brainstem response (ABR) 34

Coal tar cream can be applied to scaling areas and removed several hours later by shampooing

van Londen GJ, Perera S, Vujevich K, et al

doi: 10.1016/j.envpol.2014.06.010 105 VargJ

& Webster, T

Aon et al