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EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA)

MOTS-c (short for mitochondrial open-reading-frame of the 12S rRNA type-c) is often dubbed a mitokine a peptide hormone produced by mitochondria that influences metabolism throughout the body

At very high concentrations, copper can theoretically act as a pro-oxidant, but well-formulated products are designed to remain within the safe and effective range

The cycling rationale differs from MOTS-c's pharmaceutical cousin metformin, which is taken continuously

Persistent or severe symptoms suggest dose reduction or potential sensitivity

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