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12 , e1005679 (2016)

I am taking Ashwagandha (herbal)
- This contributes to the state of chronic inflammation that negatively affects adipose tissue functions

It has been extensively studied in pre-clinical models across gastrointestinal, musculoskeletal, and neurological research contexts

The clinical data showed the 4 mg group achieving 17.1% body weight reduction at 48 weeks, which already exceeds what most single-receptor GLP-1 agonists deliver at their maximum doses

These arent hard contraindications, but theyre situations where extra caution makes sense
