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Previous studies reported that the presence of curcuminoids is associated with anti-inflammatory capacity, which is attributed to a reduction in lipid peroxidation, inhibition of the binding of the transcription factor NF-B (nuclear factor kappa B) to DNA, leading to a decrease in pro-inflammatory cytokine concentrations, as well as a reduction in circulating inflammatory levels of gamma interferon and inhibition of COX-1 (cyclooxygenase-1 enzyme), COX-2 (cyclooxygenase-2 enzyme), and LOX activities (7, 13, 53, 58)

Long-term trial of oral treatment of pernicious anaemia with vitamin-B12peptide

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