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These microcirculatory disturbances can be alleviated by the administration of NO donors (335, 722), while they are seriously aggravated by the administration of nonselective NOS inhibitors (904) or by eNOS gene deletion (660), which have been associated with significant enhancement of LIR-induced liver injury

However, IL-6-neutralizing antibody markedly reduced serum ALT levels in FBXL5 CD11c mice (Fig

doi: 10.1021/acs.jmedchem.7b00389 100 NeelakantanHVanceVWetzelMDWangHLMcHardySFFinnertyCCet al