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Inflammation Reduction and Pain Relief Inflammation is the bodys response to injury, but too much inflammation can slow down healing and cause chronic pain

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Over time, the accumulation of these traumatic events may lead to the development of CTE, a progressive, neurodegenerative disease induced by repeated blows to or rapid displacement of the head, producing chronic changes in cognition, memory, and mood (6)

On the other hand, Mulcahy et al described a critical distal ARE element (ARE4), located ~ 3.1kb upstream of the transcriptional start site, which mediated constitutive and -NF inducible expression in HepG2 cells (Mulcahy et al., 1997)

DNA damage accumulates over time