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A significant increased risk of PD was observed in women who had the CYP1A2 polymorphism, whereas NAT2, ESR1, and ESR2 had marginal effects on PD risk (Palacios et al., 2010)

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These observations would set the scene for the next 30 + years (Potera, 2010)

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68,69 Conversely, CKD in its later stages also increases the risk of bleeding due to platelet dysfunction