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Conversely, some evidence indicated that an initial increase in respiration and presumably mitochondrial function driven by BCR crosslinking needed a costimulatory signal from CD40 or TLR9 to be maintained on the first day [76]
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Membrane associated CD14 forms a receptor complex with TLR4 (a pattern recognition receptor) and Myeloid differentiation 2 (MD2) and plays an important role in binding LPS, as well as initiating the immune response
doi: 10.1016/j.cellsig.2011.03.004
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Environ Sci Pollut Res Int 22(22):1803118039
