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There is an incomplete understanding, particularly in non-murine models, of dosetoxicity and doseefficacy relationships

Microsc Res Tech 86:13781390 He Y, Xi J, Fang J, Zhang B, Cai W (2023) Aloe-emodin alleviates doxorubicin-induced cardiotoxicity via inhibition of ferroptosis

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The fact that few differences were found between the LPS-treated and untreated samples was somewhat surprising, as LPS treatment has previously been shown to increase glutathionylation of a number of proteins in mouse macrophages 25

The majority of included patients, 73 out of 91 cases, had viral-induced ALF