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Multi-walled carbon nanotubes (MWCNTs) with mitochondria-targeted fluorescent rhodamine-110 colocalize 80% with mitochondria and exhibit superior efficacy to drugs without PtBz (152)

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Another way for HBx to induce oxidative stress is the suppression of proteins indirectly involved in the antioxidant defence, as observed in HBx-transfected HepG2 cells for the inhibition of selenoprotein P (SeP) [276] and in HBV-transgenic mice for selenium-binding protein 2 (Selenbp2) [274]

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ENVIRONMENTAL COPPER All heavy metals, including copper, originated in the universe, produced from helium and hydrogen through nuclear fusion in stars and supernova explosions before arriving on Earth around 13.7 billion years ago [10]

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