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Metabolomic analyses have demonstrated that DRP-104 inhibits Gln metabolism in tumors and reduces the production of immunosuppressive metabolites

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doi: 10.1038/s41574-019-0218-2 63 MaennerM

157 MMT exhibits minimal systemic absorption due to its inability to permeate the GI epithelium, ensuring its elimination alongside adsorbed toxins without interfering with normal bowel function