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The second stage consists of pathophysiological events caused by blood components and their metabolites, including BBB destruction, neural excitatory events, ion disturbances, oxidative stress, neuroinflammation, cell death, etc (Magid-Bernstein et al., 2022)

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Dosing in Research Studies Researchers typically begin with low doses of retatrutide, adjusting as needed based on observed responses

Liu Y, Chen H, Hao J, Li Z, Hou T, Hao H