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The results showed that the highest identification score was observed for adenine (score = 1.79), indicating a highly reliable identification

Conversely, inhibition of mitophagy can lead to mitochondrial dysfunction, trigger apoptosis, and ultimately increase treatment sensitivity [46]

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Integrating sputum analysis with omics techniques such as proteomics, transcriptomics [13], and lipidomics [14] allows for a comprehensive exploration of COPD biomarkers

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Therefore, targeting the dysfunctional mitochondria accompanying ROS imbalance and regulating antioxidant enzymes are potential targets to enhance bone health