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Metformin (for diabetes), proton pump inhibitors (such as omeprazole or esomeprazole), and H2 blockers (such as famotidine) can all reduce B12 absorption over time

[DOI] [PMC free article] [PubMed] [Google Scholar] 386.Talati M., Meyrick B., Peebles R.S., Davies S.S., Dworski R., Mernaugh R., Mitchell D., Boothby M., Roberts L.J., Sheller J.R

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B-12 injections can help with: Fatigue and low energy Mood instability or brain fog Sluggish metabolism Pernicious anemia or dietary deficiency Support during weight loss or physical recovery What Our Patients Say Thorough, professional, and kind

This applies especially to those on a vegetarian or vegan diet
