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In PD, mutations in GBA, ATP13A2, and PARK9 impair lysosomal function, leading to -synuclein accumulation and cellular toxicity (Behl et al., 2022

10.4062/biomolther.2021.155 50 JinX.WanQ

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doi: 10.1093/pcp/pcu007

Dosage and administration : to be prescribed by physician

Amyloid-beta-induced occludin down-regulation and increased permeability in human brain endothelial cells is mediated by MAPK activation
