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[DOI] [PMC free article] [PubMed] [Google Scholar] 74.Cesarone M.R., Belcaro G., Hu S., Dugall M., Hosoi M., Ledda A., Feragalli B., Maione C., Cotellese R

Unverified anecdotal reports from online forums mention various effects, though these cannot be confirmed without proper clinical investigation and may not represent causal relationships: Unverified reports of hormonal changes : Some users mention changes in libido or sexual function, though no causality has been established Theoretical cardiovascular concerns : Based on its purported vascular effects, though no clinical evidence exists Injection site reactions : Pain, redness, or swelling when administered subcutaneously Gastrointestinal symptoms : Nausea or abdominal discomfort in some reports Unknown long-term effects : No data exists on prolonged use or cumulative toxicity A significant safety concern involves product quality and contamination

2020 Oct;46(4):1347-1358

Br J Exp Pathol

Many people are eager to see results quickly and skip the lower doses, but the microdosing and titration data shows that gradual escalation produces better long-term outcomes
