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Furthermore, mitochondrial dysfunction may lead to increased ROS/RNS levels, causing telomere damage and epigenetic modifications

26) Das P, Zerda R, Alvarez FJ, Tietz EI

However, a growing body of research shows that OTC drugs are anything but harmless

This binding modes also display important contacts in the Hydrophobic cleft, the spermidine and Z subsites (see Table 4)

Hydroquinones are not redox-stable and in some condition metabolism by NQO1 yields an additional active sutrates [ 2 ]

compounded drugs are not subject to this requirement