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IF may also enhance metabolic health and strengthen resilience against chronic inflammatory conditions, such as diabetes and cardiovascular diseases, by reducing the accumulation of cellular debris [30]

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Materials and methods Literature search and data extraction We performed a pooled analysis of published articles in PubMed,Embase, Web of Science, and CNKI database for studying the association between the MTHFR C677T variant and folate content and colorectal cancer

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