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The risk of developing severe side effects is very low with only 1 in 500 patients experiencing serious adverse events and the potential benefits of the treatment are very high, especially for those who have found that no other treatments are effective

Routine Prophylaxis Study In a multicenter, open-label, prospective, randomized, controlled postmarketing clinical trial of ADVATE use in two prophylactic treatment regimens compared to that of on-demand treatment, 53 PTPs with severe to moderately severe hemophilia A (FVIII level 2 IU/dL) were analyzed in the per-protocol group

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Progress is being made by the neurofibromatosis research community towards addressing the current knowledge gaps with different resources available for cNF research (Table 2)