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These include people with inherited metabolic disorders, severe malnutrition, kidney disease requiring dialysis, liver disease, or gastrointestinal conditions that reduce nutrient absorption

La L-carnitina ejerce un efecto amortiguador que ayuda a atenuar esta acumulacin

doi: 10.2165/00007256-200636050-00005

Some people report benefit when switching formulations such as acetyl L-carnitine or propionyl L-carnitine

Trends Anal Chem 39:180194 DAcquarica A, Gasparrini F, Misiti D, Villani C, Carotti A, Cellamare S, Muck S (1999) Direct chromatographic resolution of carnitine and O-acylcarnitine enantiomers on a teicoplanin-bonded chiral stationary phase

Secondary endpoints At 12 months after baseline 7 not treated subjects (16.7%) were self-sufficient, as compared to 2 (4.7%) treated subjects ( p = 0.0719, adj