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Generally, reassess every 6-12 months
SIRT5 regulates the NRF2/HO-1 pathway in a ROS-dependent manner to inhibit cisplatin (CDDP)-induced DNA damage, thereby promoting CDDP resistance in ovarian cancer (OC) [77]
CLSM images showed the presence of lipid peroxides throughout the cancer cells upon treatment with Ru(II)-OH, NP2, or NP4 (Fig
Bouvier E, Brouillard F, Molet J et al (2017) Nrf2-dependent persistent oxidative stress results in stress-induced vulnerability to depression
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(Phila.) 2019;57(6):380386
