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In LY46, DEMs enriched in pyrimidine metabolisms, nucleotide metabolisms, valine, leucine, and isoleucine degradation, glucosinolate biosynthesis and 2-oxocarboxylic acid metabolisms were upregulated, with downregulation in tryptophan metabolism, cysteine and methionine metabolism, biosynthesis of amino acids, and related pathways (Fig

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In proximity labeling experiments, BirA has a high local concentration because the protein of interest that it is fused to is interacting with other proteins that BirA is biotinylating